Octagon was founded on scientific insights developed at Harvard. The founding team has a passion for developing new medicines and believes that people living with autoimmunity deserve better treatment options. Octagon is based in downtown Providence, RI and has lab space at The Engine in Cambridge, USA.

Octagon’s team is deeply committed to developing new medicines for diseases with unmet clinical need. The management team includes highly skilled scientists, clinicians, and entrepreneurs with decades of research experience and deep expertise in drug development.  The scientific team is growing and continues to add top research talent.

Leadership Team

Isaac Stoner, MBAPresident & CEOA biomedical engineer by training, Mr. Stoner has spent his career building new companies based on powerful scientific insights as an operator and investor.

Isaac Stoner, MBA

Co-founder & CEO

Nat Sherden, PhD

VP Chemistry

Shen (Peter) Yu, PhD

Co-founder & CTO

Michael Elliott, MBBS PhD

Scientific and Clinical Advisor

Brent Cezairliyan, PhD

VP Biology

Scientific Advisory Board

Luis Castillo, PhD

Head of Platform

Shiv Pillai, MD, PhD

Professor of Medicine, Harvard Medical School

Gregg Silverman, MDMYU Langone, Professor of Medicine, Professor of Pathology

Gregg Silverman, MD

NYU Langone, Professor of Medicine, Professor of Pathology

Iain Kilty, PhDCSO Quench Bio

Iain Kilty, PhD

CSO Sitryx

Fred Ausubel, PhD

Professor of Genetics, Harvard Medical School (Emeritus)

Co-founder

Partners Include

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